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蒋爱芹

文章来源:澳门十大正规平台网站 发布时候: 2019-09-01阅读次数: 537

研讨生导师简介

姓名

蒋爱芹

研讨标的目的

肿瘤靶向医治研讨

接洽体例

Email: jianaq@doremond.com

手机: 13914751630 (微信)

学术兼职:

中国细胞生物学会会员

小我简介


1.任务简历

2009-至今    澳门十大正规平台网站  讲师、副传授

2005-2009年    南京大学份子医学研讨所 讲师


2.科研环境简介

首要处置肿瘤的医治研讨。以第一作者或通信作者身份在SCI收录杂志上颁发论文计20篇。掌管国度天然科学基金1项,教导部课题1项,南京大学中心高校名目多项和双创名目1项。


3.研讨乐趣:

 (1) 天然产品或化学分解来源的抗肿瘤靶向药物的研讨

2三阳性乳腺癌药物的研讨



代表性论文[5年通信作者和第一作者]

1Ya-LinQi, LongGuo, Li-LiChen, HuaLi, Yu-ShunYang, Ai-QinJiang, Hai-LiangZhu. Recent progress in the design principles, sensing mechanisms, and applications of small-molecule probes for nitroreductases. Coordination Chemistry Reviews, 2020, 421: 213460. (通信作者,IF 15.367)

2Ya-Liang Zhang, Bo-Yan Li, Rong Yang, Lin-Ying Xia, A-Li Fan, Yi-Chun Chu, Lin-Jian Wang, Zhong-Chang Wang,Ai-QinJiang, Hai-Liang Zhu. A class of novel tubulin polymerization inhibitors exert effective antitumor activity via mitotic catastrophe. European Journal of Medicinal Chemistry. 2019, 163, 896-910. (通信作者,IF 5.572)

3Ya-Liang Zhang, Rong Yang, Lin-Ying Xia, Ruo-Jun Man, Yi-Chun Chu, Ai-Qin Jiang, Zhong-Chang Wang, Hai-Liang Zhu. Synthesis, anticancer activity and molecular docking studies on 1,2-diarylbenzimidazole analogues as anti-tubulin agents. Bioorganic Chemistry 2019, 92: 103219. (通信作者,IF 4.831)

4Ruo-Jun Man, Ya-Liang Zhang,Ai-Qin Jiang,Hai-Liang Zhu. A patent review of RAF kinase inhibitors (2010–2018), Expert Opinion on Therapeutic Patents, 2019, 29:675-688.(通信作者,IF 5.611

5Chun Xu, Mao Xia, Gang Meng, Chunyan Li,Aiqin Jiang, Jiwu Wei. Carrier Cells for Delivery of Oncolytic Measles Virus into Tumors Determinants of Efficient Loading. Virologica Sinica2018, 33:234–240.(通信作者,IF 3.242

6Ya-JuanQin, Yu-jingLia, Ai-QinJiang, Meng-RuYangQi-ZhangZhuHongDong, Hai-LiangZhu. Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors. European Journal of Medicinal Chemistry. 2015, 94: 447-457. (通信作者,IF 5.572

7Yu-Jia Ren, Zhong-Chang Wang, Xin Zhang, Han-Yue Qiu, Peng-Fei Wang, Ai-Qin Jiang, Hai-Liang Zhu. EGFR/HER-2 inhibitors:synthesis, biological evaluation and analysis of dihydropyridine-containing thiazolinone derivatives. RSC Adv. 2015, 5: 21445-21454. (通信作者, IF 3.119

(8) Jin-Hong Liu, Zi-Fei Zhu, Jia Tang, Ai-Qin Jiang, Liu-Fang Hua, Li Chen. Novel NO-releasing derivatives of betulinic acid with antitumor activity. Chinese Chemical Letters, 2015, 26:759–762. (通信作者, IF 4.632

9) Chun yan LiGang MengLei SuAiping ChenMao XChun XuDecai Yu, Aiqin JiangJiwu WeiDichloroacetate blocks aerobic glycolytic adaptation toattenuated measles virus and promotes viral replication leadingto enhanced oncolysis in glioblastomaOncotarget20156: 1544-1555. (通信作者)

(10) Aiqin JiangWenbo JinFeng ZhaoZiyong SunJianning LiuSplit Ssp DnaB mini-intein mediated production of recombinant human glucagon-like peptide-1/7-36Biotechnology and Applied Biochemistry201562: 309-315. (第一作者, IF 2.277




承当科研名目[名目担任人]

1南京大学双创基地重点名目0214 1499 9103新型抗肿瘤生物医药研发及财产化平台建设

2、南京大学2020年中心高校重点名目培养打算 天然产品来源的药物对三阳性乳腺癌按捺感化的挑选及机制研讨

3、国度天然科学青年基金名目81301943自噬调控溶瘤麻疹病毒疫苗株复制及溶瘤的机制研讨

4、教导部博士点新教员基金20120091120023Sirt6: 一个潜伏的抑癌基因对肿瘤停止调控的研讨

5、中心高校根基科研营业技术立异名目021414380114基于免疫引诱小搅扰RNA的抗肿瘤新药研发2015/10-2016/10

6、中心高校根基科研营业苗圃名目021414340243自噬调控溶瘤麻疹病毒疫苗株复制及溶瘤的机制研讨 2014/01-2014/12

7、中心高校根基科研营业苗圃名目 020620130633自噬调控溶瘤麻疹病毒疫苗株复制及溶瘤的机制研讨2013/01-2013/12

8、中心高校根基科研营业自在摸索名目021414340078Intein卵白介导的重组卵白药物制备研讨




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